Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099649 | 0.81 | MAPT (0.33) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL23571406 | 0.78 | TRPA1 (0.37) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31210532 | 0.78 | RXFP1 (0.45) | PIK3R1PIK3CAKDM4EALDH1A1LMNA | |
| SCHEMBL21455659 | 0.76 | KDM4E (0.43) | PTGER1MAPTNPC1AHRRAB9A | |
| SCHEMBL31309554 | 0.74 | MYC (0.41) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11707005 | 0.73 | KDM4E (0.55) | MAPTNPC1AHRRAB9ASMN1; SMN2 | |
| SCHEMBL23571672 | 0.71 | PTGER1 (0.36) | PTGER1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19222080 | 0.71 | GRM5 (0.36) | MAPTNPC1AHRRAB9ASMN1; SMN2 | |
| SCHEMBL25095788 | 0.71 | PIK3R1 (0.35) | PIK3R1PIK3CAKDM4EALDH1A1LMNA | |
| SCHEMBL5411738 | 0.70 | ALPL (0.33) | SMN1; SMN2KDM4EALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930062-A1 | Compositions containing imidazo-pyridine derivatives for dying keratinous fibres and process | L'OREAL (FR) | 1999-07-21 | — | — | EP | claimed |
| US-5980585-A | NONTOXIC; HAIR DYE | L'OREAL (FR) | 1999-11-09 | — | — | US | disclosed |
| EP-0930062-A1 | Compositions containing imidazo-pyridine derivatives for dying keratinous fibres and process | L'OREAL (FR) | 1999-07-21 | — | — | EP | disclosed |
| EP-0299470-B1 | Imidazo[1,2-a]pyridines | BYK GULDEN LOMBERG CHEM FAB (DE) | 1996-12-04 | — | — | EP | disclosed |
| US-5112834-A | Antisecretory and antiulcer | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-05-12 | — | — | US | disclosed |
| EP-0370056-A1 | NEW DIAZOLS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1990-05-30 | — | — | EP | disclosed |
| WO-1989000570-A1 | NEW DIAZOLS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299470-A1 | Imidazo[1,2-a]pyridines | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1989-01-18 | — | — | EP | disclosed |