Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420845 | 1.00 | EPHX1 (0.52) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL5698801 | 1.00 | EPHX1 (0.52) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL18944802 | 1.00 | EPHX1 (0.52) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL1644134 | 1.00 | EPHX1 (0.52) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL3421829 | 1.00 | EPHX1 (0.52) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL9099579 | 1.00 | EPHX1 (0.52) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL27395436 | 1.00 | EPHX1 (0.52) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL6237122 | 0.92 | CA2 (0.43) | EPHX1MAPTHSD17B10GMNNTP53 | |
| Butyric Acid SCHEMBL29174521 | 0.91 | GPR84 (0.47) | EPHX1MAPTHSD17B10GMNNTP53 | |
| Butyric Acid SCHEMBL22772258 | 0.91 | GPR84 (0.47) | EPHX1MAPTHSD17B10GMNNTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498786-A | Synthesis of intermediates in the preparation of ACAT inhibitors | PFIZER INC. (US) | 1996-03-12 | — | — | US | disclosed |
| WO-1992013843-A1 | SYNTHESIS OF INTERMEDIATES IN THE PREPARATION OF ACAT INHIBITORS | PFIZER INC. (US) | 1992-08-20 | — | — | WO | disclosed |