SCHEMBL9099896

SCHEMBL9099896

CCCCOC(=O)c1cccc(C=O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.54
CYP1A2 P05177 3/20 0.53
CYP2C19 P33261 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
CYP2C9 P11712 2/20 0.53
NPC1 O15118 1/20 0.53
HPGD P15428 1/20 0.53
RAB9A P51151 1/20 0.53
ESR1 P03372 8/20 0.53
LMNA P02545 4/20 0.53
TSHR P16473 3/20 0.53
CYP2D6 P10635 1/20 0.53
MAPK1 P28482 1/20 0.53
NR1H2 P55055 1/20 0.53
RNASEL Q05823 1/20 0.53
TDP1 Q9NUW8 1/20 0.51
CYP3A4 P08684 1/20 0.51
PDE4D Q08499 1/20 0.51
UNG P13051 1/20 0.50
TP53 P04637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9097542 0.96 LMNA (0.53) CYP1A2CYP2C19SMN1; SMN2CYP2C9NPC1
SCHEMBL9099005 0.94 LMNA (0.56) NPC1RAB9AESR1LMNATSHR
SCHEMBL9097849 0.91 LMNA (0.60) SMN1; SMN2NPC1HPGDRAB9AESR1
SCHEMBL111861 0.86 L3MBTL1 (0.64) L3MBTL1CYP1A2CYP2C19SMN1; SMN2CYP2C9
SCHEMBL11360450 0.86 KDM4E (0.55) L3MBTL1CYP1A2CYP2C19SMN1; SMN2CYP2C9
SCHEMBL11360451 0.86 KDM4E (0.55) L3MBTL1CYP1A2CYP2C19SMN1; SMN2CYP2C9
SCHEMBL1802617 0.84 ESR1 (0.61) L3MBTL1CYP1A2CYP2C19SMN1; SMN2CYP2C9
SCHEMBL97218 0.84 POLB (0.57) CYP1A2CYP2C19SMN1; SMN2CYP2C9NPC1
Lithium SCHEMBL30876327 0.84 L3MBTL1 (0.62) L3MBTL1CYP1A2CYP2C19SMN1; SMN2CYP2C9
SCHEMBL7189257 0.84 L3MBTL1 (0.62) L3MBTL1CYP1A2CYP2C19SMN1; SMN2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390668-A Compound with ketoxime ether structure and application thereof 复旦大学 2025-02-07 CN disclosed
US-9382496-B1 Lubricants with high thermal stability for heat-assisted magnetic recording WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2016-07-05 US disclosed
US-9382496-B1 Lubricants with high thermal stability for heat-assisted magnetic recording WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2016-07-05 US disclosed
US-9382496-B1 Lubricants with high thermal stability for heat-assisted magnetic recording WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2016-07-05 US disclosed
CN-104411707-A Substituted phenylimidazopyrazoles and their use Bayer Pharma AG 2015-03-11 CN disclosed
EP-0323441-B1 5-Fluorouracil derivatives OTSUKA PHARMA CO LTD (JP) 1996-04-24 EP disclosed
EP-0436902-B1 5-Fluorouracil derivatives OTSUKA PHARMA CO LTD (JP) 1995-06-28 EP disclosed
US-5155113-A Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-10-13 US disclosed
EP-0180188-B1 A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-04-15 EP disclosed
EP-0180897-B1 5-FLUOROURACIL DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-08-07 EP disclosed
EP-0436902-A1 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-07-17 EP disclosed
US-4983609-A Anticancer agents OTSUKA PHARMACEUTICAL (JP) 1991-01-08 US disclosed
US-4864021-A ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-09-05 US disclosed
EP-0323441-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-07-05 EP disclosed
EP-0180897-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-14 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed
US-4271186-A Stilbene compounds and insecticidal/acaricidal compositions BAYER AKTIENGESELLSCHAFT (DE) 1981-06-02 US disclosed