Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698682 | 0.89 | BCHE (0.46) | BCHEACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL3696486 | 0.89 | BCHE (0.48) | BCHEACHEHTR2ATRPV1MEN1 | |
| SCHEMBL9108331 | 0.89 | BCHE (0.49) | BCHEACHEHTR2ATRPV1MEN1 | |
| SCHEMBL3702471 | 0.84 | BCHE (0.49) | BCHEACHEMEN1KMT2AMTNR1A | |
| SCHEMBL9101126 | 0.83 | HTR2A (0.45) | BCHEACHEHTR2ATRPV1MEN1 | |
| SCHEMBL3704087 | 0.83 | TAAR1 (0.44) | ALDH1A1 | |
| SCHEMBL9102425 | 0.82 | MAPT (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3706882 | 0.82 | HTR2A (0.46) | BCHEACHEHTR2ATRPV1KMT2A | |
| SCHEMBL9102458 | 0.80 | MAPT (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9103931 | 0.79 | ITGB2 (0.44) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460798-A2 | APAF-1 INHIBITOR COMPOUNDS | Laboratorios SALVAT, S.A. (ES) | 2012-06-06 | — | — | EP | disclosed |