Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.37 |
| ▸ | ITGAL | P20701 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102425 | 0.92 | MAPT (0.44) | ALDH1A1KDM4EMAPTSMN1; SMN2ITGB2 | |
| SCHEMBL3701945 | 0.91 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDP2RX7MAPT | |
| SCHEMBL9102458 | 0.89 | MAPT (0.42) | ALDH1A1KDM4EMAPTITGB2ICAM1 | |
| SCHEMBL3702498 | 0.87 | HPGD (0.39) | TAAR1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3698682 | 0.86 | BCHE (0.46) | ALDH1A1HDAC8NPC1RAB9A | |
| SCHEMBL3702975 | 0.85 | HPGD (0.44) | TAAR1ALDH1A1KDM4EHPGDP2RX7 | |
| SCHEMBL9103931 | 0.84 | ITGB2 (0.44) | ALDH1A1MAPTSMN1; SMN2ITGB2ICAM1 | |
| SCHEMBL3698675 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDP2RX7MAPT | |
| SCHEMBL3700824 | 0.84 | ITGB2 (0.37) | ALDH1A1KDM4EMAPTSMN1; SMN2ITGB2 | |
| SCHEMBL9105229 | 0.84 | ITGB2 (0.39) | ALDH1A1KDM4EMAPTSMN1; SMN2ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040701-B2 | Apaf-1 inhibitor compounds | LABORATORIOS SALVAT, S.A. (ES) | 2015-05-26 | — | — | US | disclosed |
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | LABORATORIOS SALVAT, S.A. (ES) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | APAF1, API5, AIFM1 | TAAR1 4146/4885ALDH1A1 701/4885KDM4E 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.