SCHEMBL9100264

SCHEMBL9100264

CCCCc1ccc2c(c1)Oc1ccc(CCCC)cc1N2OS(=O)(=O)CCC

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SKP2 Q13309 1/20 0.31
FFAR1 O14842 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30
HPGD P15428 1/20 0.30
TRIM24 O15164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9101890 0.93 CA2 (0.31) CA2
SCHEMBL9104010 0.92 P2RX4 (0.36) CA2SMN1; SMN2
SCHEMBL9102037 0.92 P2RX4 (0.36) CA2SMN1; SMN2
SCHEMBL9102665 0.89 KDM4E (0.31) CA2
SCHEMBL9547678 0.86 CA2 (0.30) CA2SMN1; SMN2
SCHEMBL9103982 0.85 P2RX4 (0.34)
SCHEMBL9107635 0.85 P2RX4 (0.34)
SCHEMBL9104833 0.84 CA2 (0.30) CA2SMN1; SMN2
SCHEMBL9102597 0.83 HTR1A (0.31)
SCHEMBL9106662 0.81 P2RX4 (0.35) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed