Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712213 | 0.87 | NOS3 (0.45) | EPHX2NOS3NOS1NOS2TP53 | |
| SCHEMBL658618 | 0.82 | NOS3 (0.38) | EPHX2NOS3NOS1NOS2TP53 | |
| SCHEMBL7100547 | 0.82 | NOS3 (0.38) | EPHX2NOS3NOS1NOS2TP53 | |
| SCHEMBL780172 | 0.81 | NOS3 (0.38) | EPHX2NOS3NOS1NOS2TP53 | |
| SCHEMBL9100947 | 0.80 | PPIA (0.36) | EPHX2NOS1TSHRLMNAKMT2A | |
| SCHEMBL361128 | 0.80 | PTGDR2 (0.49) | EPHX2TP53CASP1PTGDR2SMN1; SMN2 | |
| SCHEMBL9100301 | 0.80 | HSP90AA1 (0.47) | EPHX2NOS3NOS1NOS2SMN1; SMN2 | |
| SCHEMBL8076430 | 0.79 | NOS3 (0.41) | EPHX2NOS3NOS1NOS2SMN1; SMN2 | |
| SCHEMBL5278348 | 0.78 | PTGDR2 (0.47) | EPHX2NOS3NOS1NOS2TP53 | |
| SCHEMBL2217850 | 0.77 | PTGDR2 (0.46) | EPHX2NOS3NOS1NOS2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489501-A | MIXTURES OF TWO COORDINATION COMPOUNDS WHICH REACT TO FORM NEW COORDINATION COMPOUND WHILE CAUSING VISIBLE COLOR CHANGES | RICOH COMPANY, LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| US-5446011-A | Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid | RICOH COMPANY, LTD. (JP) | 1995-08-29 | — | — | US | disclosed |