Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | PCNA | P12004 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103877 | 0.89 | USP2 (0.45) | ALDH1A1USP2ESRRGMTNR1AMTNR1B | |
| SCHEMBL9100817 | 0.75 | HPGD (0.48) | MAPT | |
| SCHEMBL22015434 | 0.71 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL9099535 | 0.71 | USP2 (0.57) | ALDH1A1MAPTSMN1; SMN2USP2MTNR1A | |
| SCHEMBL9102402 | 0.70 | USP2 (0.44) | ALDH1A1MAPTLMNAUSP2 | |
| SCHEMBL27624379 | 0.70 | ACACB (0.64) | NPC1RAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL9101010 | 0.68 | USP2 (0.47) | ALDH1A1MAPTLMNASMN1; SMN2USP2 | |
| SCHEMBL8615220 | 0.67 | NQO1 (0.54) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL7195854 | 0.67 | NR5A1 (0.62) | MAPTSMN1; SMN2LTA4H | |
| SCHEMBL7197958 | 0.67 | NR5A1 (0.62) | MAPTSMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474431-B1 | Amphiphilic compounds for sequential monolayer deposition | ICI PLC (GB) | 1996-03-06 | — | — | EP | disclosed |
| US-5275924-A | Non-centrosymmetric; hydrophobic; chromophores | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-04 | — | — | US | disclosed |
| EP-0474431-A1 | Amphiphilic compounds for sequential monolayer deposition | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |