Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101089 | 0.89 | ALDH1A1 (0.43) | USP2ESRRGMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL9100817 | 0.81 | HPGD (0.48) | GAADNM1HSD17B10CA12CA1 | |
| SCHEMBL9099535 | 0.80 | USP2 (0.57) | USP2BCHEMTNR1AMTNR1BGAA | |
| SCHEMBL9102402 | 0.79 | USP2 (0.44) | USP2BCHEGAAALDH1A1HSD17B10 | |
| SCHEMBL9101010 | 0.75 | USP2 (0.47) | USP2BCHEMTNR1AMTNR1BGAA | |
| SCHEMBL1986412 | 0.71 | GAA (0.57) | GAADNM1HDAC1HDAC6HDAC8 | |
| SCHEMBL9103803 | 0.71 | CYP1A1 (0.53) | ESRRGGAAHDAC6ESRRBALDH1A1 | |
| SCHEMBL9549340 | 0.71 | DNM1 (0.62) | USP2BCHEGAADNM1 | |
| SCHEMBL2012086 | 0.71 | ACKR3 (0.54) | USP2BCHEMTNR1AMTNR1BGAA | |
| SCHEMBL4861149 | 0.71 | USP2 (0.57) | USP2BCHEMTNR1AMTNR1BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474431-B1 | Amphiphilic compounds for sequential monolayer deposition | ICI PLC (GB) | 1996-03-06 | — | — | EP | disclosed |
| US-5275924-A | Non-centrosymmetric; hydrophobic; chromophores | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-04 | — | — | US | disclosed |
| EP-0474431-A1 | Amphiphilic compounds for sequential monolayer deposition | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |