Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105339 | 0.89 | KMT2A (0.45) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL4568384 | 0.87 | MEN1 (0.44) | KMT2AMEN1TDP1HTR1AALDH1A1 | |
| SCHEMBL10179873 | 0.82 | MCHR1 (0.42) | KMT2AMEN1LCKFYNDAO | |
| SCHEMBL6117616 | 0.77 | KMT2A (0.38) | KMT2AMEN1TDP1LCKFYN | |
| SCHEMBL4568376 | 0.73 | MEN1 (0.43) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL4568370 | 0.69 | SMN1; SMN2 (0.38) | KMT2AMEN1TDP1LCKFYN | |
| SCHEMBL8761820 | 0.69 | USP2 (0.38) | KMT2AMEN1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL4568025 | 0.69 | KMT2A (0.38) | KMT2AMEN1MAPTPOLBL3MBTL1 | |
| SCHEMBL6118174 | 0.69 | MAPT (0.56) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL9103819 | 0.68 | LMNA (0.42) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460791-A1 | INDOLE DERIVATIVE AND PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-06-06 | — | — | EP | disclosed |