Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101213 | 0.89 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10179873 | 0.81 | MCHR1 (0.42) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL9103819 | 0.80 | LMNA (0.42) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9105929 | 0.78 | MAPK1 (0.50) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6118214 | 0.77 | HTR1A (0.34) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4568384 | 0.77 | MEN1 (0.44) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL4324973 | 0.70 | KDM4E (0.68) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6117825 | 0.69 | KDM4E (0.54) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9101460 | 0.69 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6117616 | 0.69 | KMT2A (0.38) | KMT2AMEN1SMN1; SMN2TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460791-A1 | INDOLE DERIVATIVE AND PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-06-06 | — | — | EP | disclosed |