Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465523 | 0.79 | HSD11B1 (0.39) | — | |
| SCHEMBL1692246 | 0.78 | SLC6A4 (0.41) | — | |
| SCHEMBL4698997 | 0.74 | BACE1 (0.39) | BACE1 | |
| SCHEMBL4946908 | 0.74 | TSHR (0.41) | HCAR3HCAR2 | |
| SCHEMBL9608820 | 0.73 | HSD11B1 (0.40) | — | |
| SCHEMBL4701589 | 0.72 | ICMT (0.42) | BACE1 | |
| SCHEMBL10269088 | 0.68 | — | — | |
| SCHEMBL21961580 | 0.67 | SLC6A4 (0.45) | BACE1 | |
| SCHEMBL3327547 | 0.66 | CHRNA1 (0.47) | HCAR3HCAR2BACE1 | |
| SCHEMBL27631414 | 0.66 | HCAR2 (0.38) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702678-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029291-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |