Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15229567 | 0.90 | HTT (0.40) | HTTALDH1A1HSD17B10SNCALMNA | |
| SCHEMBL17417188 | 0.89 | HTT (0.54) | HTTALDH1A1HSD17B10SNCALMNA | |
| SCHEMBL1225025 | 0.87 | HTT (0.38) | HTTALDH1A1HSD17B10SNCALMNA | |
| SCHEMBL4026469 | 0.85 | HTT (0.41) | HTTALDH1A1HSD17B10SNCALMNA | |
| SCHEMBL775990 | 0.85 | HTT (0.41) | HTTALDH1A1HSD17B10SNCALMNA | |
| SCHEMBL776507 | 0.83 | HTT (0.39) | HTTALDH1A1HSD17B10SNCALMNA | |
| SCHEMBL29029868 | 0.83 | LMNA (0.41) | HTTALDH1A1HSD17B10SNCALMNA | |
| SCHEMBL2058168 | 0.82 | HTT (0.40) | HTTALDH1A1HSD17B10SNCALMNA | |
| SCHEMBL9615906 | 0.82 | HTT (0.43) | HTTALDH1A1HSD17B10SNCALMNA | |
| SCHEMBL9614139 | 0.81 | HTT (0.42) | HTTALDH1A1HSD17B10SNCALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489501-A | MIXTURES OF TWO COORDINATION COMPOUNDS WHICH REACT TO FORM NEW COORDINATION COMPOUND WHILE CAUSING VISIBLE COLOR CHANGES | RICOH COMPANY, LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| US-5446011-A | Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid | RICOH COMPANY, LTD. (JP) | 1995-08-29 | — | — | US | disclosed |