Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971719 | 0.87 | CA2 (0.42) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL9614139 | 0.85 | HTT (0.42) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL9568576 | 0.85 | HTT (0.38) | HTTTSHRSNCAALDH1A1HSD17B10 | |
| SCHEMBL22908991 | 0.85 | RORC (0.51) | HTTTSHRALDH1A1HSD17B10RORC | |
| SCHEMBL6329340 | 0.83 | HTT (0.40) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL9101581 | 0.82 | HTT (0.43) | HTTTSHRSNCAALDH1A1HSD17B10 | |
| SCHEMBL17417188 | 0.82 | HTT (0.54) | HTTTSHRSNCAALDH1A1HSD17B10 | |
| SCHEMBL600325 | 0.82 | ALDH1A1 (0.36) | HTTTSHRSNCAALDH1A1HSD17B10 | |
| SCHEMBL15641681 | 0.81 | HTT (0.39) | HTTTSHRSNCAALDH1A1HSD17B10 | |
| SCHEMBL18776589 | 0.81 | TSHR (0.52) | HTTTSHRALDH1A1HSD17B10RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4175375-A | — | — | None | — | — | JP | disclosed |
| JP-H04175375-A | THERMOSETTING COMPOSITION | NIPPON OIL & FATS CO LTD | 1992-06-23 | — | — | JP | disclosed |