Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655250 | 0.84 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL28815008 | 0.83 | DGAT1 (0.47) | DGAT1CA1CA2CA7MEN1 | |
| SCHEMBL8632717 | 0.83 | DGAT1 (0.41) | DGAT1CA1CA2CA12CA14 | |
| SCHEMBL27992932 | 0.82 | DGAT1 (0.43) | DGAT1MEN1GAAKMT2ACTSK | |
| SCHEMBL27992931 | 0.82 | DGAT1 (0.43) | DGAT1MEN1GAAKMT2ACTSK | |
| SCHEMBL28842397 | 0.81 | DGAT1 (0.48) | DGAT1CA1CA2CA7CA12 | |
| SCHEMBL27575604 | 0.81 | DGAT1 (0.48) | DGAT1CA2CA12CA14 | |
| SCHEMBL27966695 | 0.81 | DGAT1 (0.48) | DGAT1CA2CA12CA14 | |
| SCHEMBL4794283 | 0.81 | DGAT1 (0.48) | DGAT1CA2CA12CA14 | |
| SCHEMBL4794280 | 0.81 | DGAT1 (0.48) | DGAT1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502036-A | VIRICIDES | BIOMEGA BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-03-26 | — | — | US | disclosed |
| EP-0411334-A1 | Antiherpes pentapeptide derivatives having a substituted aspartic acid side chain | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-02-06 | — | — | EP | disclosed |