Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100006 | 0.95 | THRB (0.31) | THRB | |
| SCHEMBL9103642 | 0.94 | THRB (0.34) | HDAC3HDAC1HDAC6THRBMAPT | |
| SCHEMBL9104426 | 0.88 | HDAC6 (0.35) | HDAC3HDAC1HDAC6THRBMAPT | |
| SCHEMBL9103457 | 0.87 | GRIA2 (0.34) | HDAC3HDAC1HDAC6MAPT | |
| SCHEMBL9103620 | 0.82 | HDAC3 (0.33) | HDAC3HDAC1HDAC6THRBMAPT | |
| SCHEMBL9100326 | 0.82 | HDAC3 (0.30) | HDAC3HDAC1HDAC6 | |
| SCHEMBL9102715 | 0.82 | HDAC6 (0.35) | HDAC3HDAC1HDAC6THRBMAPT | |
| SCHEMBL9103600 | 0.81 | CHRM1 (0.31) | — | |
| SCHEMBL9100243 | 0.81 | THRB (0.34) | HDAC3HDAC1HDAC6THRBMAPT | |
| SCHEMBL9104568 | 0.78 | BCHE (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |