Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.32 |
| ▸ | MARK4 | Q96L34 | 4/20 | 0.32 |
| ▸ | APLNR | P35414 | 3/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9104645 | 0.95 | APLNR (0.31) | APLNR | |
| SCHEMBL9104426 | 0.95 | HDAC6 (0.35) | HDAC3HDAC1HDAC6BCHEKMT2A | |
| SCHEMBL9100243 | 0.92 | THRB (0.34) | HDAC3HDAC1HDAC6BCHEKMT2A | |
| SCHEMBL9100326 | 0.89 | HDAC3 (0.30) | HDAC3HDAC1HDAC6 | |
| SCHEMBL9100006 | 0.88 | THRB (0.31) | THRB | |
| SCHEMBL9102452 | 0.86 | GRIA2 (0.40) | HDAC3HDAC1HDAC6BCHEKMT2A | |
| SCHEMBL9102352 | 0.86 | GRIA2 (0.31) | — | |
| SCHEMBL9100816 | 0.85 | HDAC1 (0.33) | HDAC3HDAC1HDAC6BCHEMARK4 | |
| SCHEMBL9099076 | 0.85 | RORB (0.35) | HDAC3HDAC1HDAC6BCHEKMT2A | |
| SCHEMBL9105077 | 0.84 | APLNR (0.34) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |