SCHEMBL9101980

SCHEMBL9101980

CCC(N1c2ccccc2Oc2c(-c3ncccc3C)cc(-c3ncccc3C)cc21)S(=O)(=O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 1/20 0.32
MAPT P10636 1/20 0.31
SMO Q99835 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9107664 0.89 CHRM1 (0.32)
SCHEMBL9102741 0.87 GRIA2 (0.38) GRIA2
SCHEMBL9103600 0.87 CHRM1 (0.31)
SCHEMBL9099967 0.85 APLNR (0.31)
SCHEMBL9103542 0.82 TP53 (0.33) MAPTSMO
SCHEMBL9104404 0.81 GRIA2 (0.38) GRIA2
SCHEMBL9103457 0.80 GRIA2 (0.34) GRIA2MAPTSMO
SCHEMBL9102286 0.77 CHRM1 (0.33)
SCHEMBL9103583 0.77 P2RX4 (0.36)
SCHEMBL9100957 0.77 P2RX4 (0.39) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed