SCHEMBL9107664

SCHEMBL9107664

CCc1cccnc1-c1cc(-c2ncccc2CC)c2c(c1)N(C(CC)S(=O)(=O)O)c1ccccc1O2

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9103600 0.94 CHRM1 (0.31) CHRM1
SCHEMBL9099967 0.92 APLNR (0.31) CHRM1
SCHEMBL9101980 0.89 GRIA2 (0.32)
SCHEMBL9102286 0.87 CHRM1 (0.33) CHRM1THRB
SCHEMBL9104679 0.82 TP53 (0.33) CHRM1THRB
SCHEMBL9100299 0.81 PDK1 (0.30) THRB
SCHEMBL9103943 0.81 CHRM1 (0.32) CHRM1
SCHEMBL9103642 0.80 THRB (0.34) THRB
SCHEMBL9105077 0.79 APLNR (0.34) CHRM1
SCHEMBL9102741 0.77 GRIA2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed