Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100735 | 0.87 | PLK1 (0.35) | PLK1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9236827 | 0.86 | CTNNB1 (0.48) | NPC1RAB9AMAPTSMN1; SMN2CTNNB1 | |
| SCHEMBL9905363 | 0.85 | PLK1 (0.40) | PLK1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL21218965 | 0.83 | PLK1 (0.32) | PLK1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5057465 | 0.83 | ABCB1 (0.48) | PLK1SMN1; SMN2 | |
| SCHEMBL667482 | 0.80 | PLK1 (0.37) | PLK1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL29684841 | 0.80 | PLK1 (0.37) | PLK1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL17416601 | 0.80 | PLK1 (0.38) | PLK1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL17416611 | 0.79 | NR1H2 (0.35) | NPC1RAB9AMAPTSMN1; SMN2CTNNB1 | |
| SCHEMBL9104632 | 0.78 | NPC1 (0.39) | NPC1RAB9AMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |