Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | USP9X | Q93008 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17416611 | 0.87 | NR1H2 (0.35) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL5057398 | 0.84 | ABCB1 (0.44) | — | |
| SCHEMBL9236827 | 0.78 | CTNNB1 (0.48) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9102042 | 0.78 | PLK1 (0.38) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL9102918 | 0.73 | HPGD (0.37) | RXFP1 | |
| SCHEMBL9101070 | 0.72 | HPGD (0.41) | NR1H2NR1H3 | |
| SCHEMBL5053791 | 0.72 | ABCB1 (0.39) | — | |
| SCHEMBL5056861 | 0.71 | HPGD (0.37) | RXFP1 | |
| SCHEMBL5062182 | 0.71 | HPGD (0.41) | NR1H2NR1H3 | |
| SCHEMBL5058572 | 0.70 | HPGD (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |