Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100848 | 1.00 | CYP26B1 (0.32) | CYP26B1ALOX5PTGS1PTGS2KEAP1 | |
| SCHEMBL9097980 | 0.83 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL9097989 | 0.83 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL9050402 | 0.75 | — | — | |
| SCHEMBL9076299 | 0.74 | ALOX5 (0.30) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9050113 | 0.74 | ALOX5 (0.30) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9076298 | 0.74 | ALOX5 (0.30) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9367656 | 0.72 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9101412 | 0.71 | ALOX5 (0.39) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9098432 | 0.71 | ALOX5 (0.42) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702678-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-03-27 | — | — | EP | claimed |
| WO-1994029291-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1994-12-22 | — | — | WO | claimed |
| EP-0702678-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029291-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |