SCHEMBL9102202

SCHEMBL9102202

CCN1c2ccccc2Sc2cccc(-c3ncccn3)c21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 6/20 0.45
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
LMNA P02545 1/20 0.41
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
HPGD P15428 3/20 0.40
PTGS1 P23219 2/20 0.40
PTGS2 P35354 2/20 0.40
HTT P42858 1/20 0.40
KDM4E B2RXH2 2/20 0.40
BCHE P06276 2/20 0.40
ALOX15 P16050 2/20 0.40
ALOX12 P18054 2/20 0.40
ACHE P22303 2/20 0.40
HSD17B10 Q99714 2/20 0.40
SLC22A1 O15245 1/20 0.40
CYP1A2 P05177 1/20 0.40
CHRM2 P08172 1/20 0.40
HTR1A P08908 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9102120 0.89 KDM1A (0.46) KDM1AKMT2AMEN1LMNAALDH1A1
SCHEMBL9104548 0.86 KDM1A (0.43) KDM1AKMT2AMEN1LMNAALDH1A1
SCHEMBL9102919 0.81 MAOA (0.53) KDM1AKMT2AMEN1LMNAALDH1A1
SCHEMBL9106588 0.76 KDM1A (0.44) KDM1AKMT2AMEN1LMNAALDH1A1
SCHEMBL9102663 0.76 TP53 (0.36) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL23308369 0.75 KDM1A (0.48) KDM1AKMT2AMEN1LMNAALDH1A1
SCHEMBL28242942 0.75 KDM1A (0.48) KDM1AKMT2AMEN1LMNAALDH1A1
SCHEMBL29557425 0.75 KDM1A (0.61) KDM1AKMT2ALMNAALDH1A1MAPT
SCHEMBL293951 0.75 KDM1A (0.61) KDM1AKMT2ALMNAALDH1A1MAPT
SCHEMBL9101733 0.73 BCHE (0.35) KDM1AKMT2ALMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed