Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 9/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | Q9HBH1 | 1/20 | 0.39 | |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9104548 | 0.90 | KDM1A (0.43) | KDM1ACYP2D6CYP1A2HIF1AKDM4E | |
| SCHEMBL9102120 | 0.87 | KDM1A (0.46) | KDM1ACYP2D6CYP2C19CYP1A2HIF1A | |
| SCHEMBL9100603 | 0.83 | MAOA (0.50) | KDM1ACYP1A2HIF1AKDM4EMAPT | |
| SCHEMBL9106477 | 0.79 | HTR7 (0.37) | CYP2D6CYP2C19CYP1A2HIF1AKDM4E | |
| SCHEMBL9102202 | 0.76 | KDM1A (0.45) | KDM1ACYP2D6CYP1A2HIF1AKDM4E | |
| SCHEMBL28043661 | 0.76 | KDM1A (0.43) | KDM1ACYP2D6CYP2C19CYP1A2HIF1A | |
| SCHEMBL31123118 | 0.74 | KDM1A (0.65) | KDM1ACYP2D6CYP2C19CYP1A2HIF1A | |
| SCHEMBL29795163 | 0.74 | KDM1A (0.65) | KDM1ACYP2D6CYP2C19CYP1A2HIF1A | |
| SCHEMBL343282 | 0.74 | KDM1A (0.65) | KDM1ACYP2D6CYP2C19CYP1A2HIF1A | |
| Ammonia Solution, Strong SCHEMBL5726715 | 0.73 | KDM1A (0.62) | KDM1ACYP2D6CYP2C19CYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |