Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5057388 | 0.92 | ABCB1 (0.56) | ABCB1HPGDSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL17416592 | 0.82 | ADRB2 (0.42) | ABCB1HPGDCYP3A4ALDH1A1LMNA | |
| SCHEMBL9714304 | 0.81 | ABCB1 (0.75) | ABCB1HPGDSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL9903862 | 0.80 | HPGD (0.63) | ABCB1HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL9714597 | 0.79 | ABCB1 (0.76) | ABCB1HPGDSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL5053798 | 0.78 | HPGD (0.43) | ABCB1HPGDSMN1; SMN2CYP3A4LMNA | |
| SCHEMBL17416639 | 0.78 | CYP1A2 (0.42) | ABCB1HPGDALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9101065 | 0.77 | HPGD (0.52) | ABCB1HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL5058555 | 0.77 | ABCB1 (0.58) | ABCB1HPGDSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9714603 | 0.77 | CYP3A4 (0.73) | ABCB1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |