Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902027 | 0.85 | CTSB (0.39) | ALDH1A1ABCB1RAB9AHPGD | |
| SCHEMBL5057388 | 0.82 | ABCB1 (0.56) | CYP1A2CYP2C9ALDH1A1LMNAABCB1 | |
| SCHEMBL9102355 | 0.78 | ABCB1 (0.63) | CYP1A2CYP2C9ALDH1A1LMNAABCB1 | |
| SCHEMBL17416592 | 0.72 | ADRB2 (0.42) | CYP1A2CYP2C9GAAALDH1A1LMNA | |
| SCHEMBL5053798 | 0.71 | HPGD (0.43) | LMNAABCB1KMT2AHPGDL3MBTL1 | |
| SCHEMBL132216 | 0.70 | TSHR (0.67) | CYP1A2CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL29385659 | 0.70 | TSHR (0.67) | CYP1A2CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL398174 | 0.68 | CYP2D6 (0.60) | CYP1A2CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL5058555 | 0.67 | ABCB1 (0.58) | CYP2C9ABCB1HPGD | |
| Hydrochloric Acid SCHEMBL4171963 | 0.67 | TSHR (0.62) | CYP1A2CYP2D6CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |