Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102469 | 1.00 | MET (1.00) | METCDKL5 | |
| SCHEMBL9102477 | 1.00 | MET (1.00) | METCDKL5 | |
| SCHEMBL9103749 | 0.89 | MET (1.00) | MET | |
| SCHEMBL9103728 | 0.89 | MET (1.00) | MET | |
| SCHEMBL9103744 | 0.89 | MET (1.00) | MET | |
| SCHEMBL12877858 | 0.86 | MET (0.75) | METCDKL5 | |
| SCHEMBL6522846 | 0.85 | MET (0.75) | METCDKL5 | |
| SCHEMBL6522843 | 0.85 | MET (0.75) | METCDKL5 | |
| SCHEMBL6522839 | 0.85 | MET (0.75) | METCDKL5 | |
| SCHEMBL1163653 | 0.85 | MET (0.73) | METCDKL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8497368-B2 | Heterocyclic hydrazone compounds | NOVARTIS AG (CH) | 2013-07-30 | — | — | US | disclosed |
| US-20120142681-A1 | HETEROCYCLIC HYDRAZONE COMPOUNDS | NOVARTIS AG (CH) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142681-A1 | HETEROCYCLIC HYDRAZONE COMPOUNDS | MET, HGF, RET | MET 1/4885CDKL5 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.