SCHEMBL9102530

SCHEMBL9102530

CCc1ccc2c(c1)N(C(CC)S(=O)(=O)O)c1c(CC)cccc1O2

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
RAB9A P51151 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
P2RX4 Q99571 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SIGMAR1 Q99720 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9100220 0.89
SCHEMBL9104702 0.88 METAP2 (0.31) P2RX4
SCHEMBL9106652 0.87 P2RX4 (0.38) MAPTRAB9AP2RX4NPC1ALDH1A1
SCHEMBL9101918 0.87 P2RX4 (0.40) MAPTP2RX4SMN1; SMN2
SCHEMBL9104818 0.86 METAP2 (0.33) P2RX4
SCHEMBL9105463 0.85
SCHEMBL9102651 0.83 HTR2A (0.31) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL9105218 0.83 P2RX4 (0.33) P2RX4
SCHEMBL9107440 0.82 P2RX4 (0.36) MAPTP2RX4SMN1; SMN2
SCHEMBL9103970 0.80 P2RX4 (0.38) MAPTRAB9AP2RX4NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed