SCHEMBL9105218

SCHEMBL9105218

CCc1cccc2c1Oc1cccc(CC)c1N2C(CC)S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 3/20 0.33
MAOA P21397 1/20 0.32
HTT P42858 1/20 0.32
P2RX1 P51575 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9101918 0.91 P2RX4 (0.40) P2RX4MAOAHTTP2RX1
SCHEMBL9103553 0.90 P2RX4 (0.39) P2RX4MAOAHTTP2RX1
SCHEMBL9102934 0.89 P2RX4 (0.33) P2RX4P2RX1
SCHEMBL9105931 0.89
SCHEMBL9105463 0.87
SCHEMBL9102664 0.87 MTNR1A (0.33) P2RX4P2RX1
SCHEMBL9102530 0.83 MAPT (0.32) P2RX4
SCHEMBL9102980 0.83 P2RX4 (0.39) P2RX4MAOAP2RX1
SCHEMBL9105388 0.82 P2RX4 (0.33) P2RX4P2RX1
SCHEMBL9103479 0.82 NPC1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed