Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
| ▸ | F3 | P13726 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103746 | 0.95 | GHSR (0.49) | GHSRAGTR1XIAPMAPTPOLB | |
| SCHEMBL9106874 | 0.94 | GHSR (0.49) | GHSRAGTR1XIAPMAPTPOLB | |
| SCHEMBL9108780 | 0.93 | GHSR (0.42) | GHSRAGTR1XIAPMAPTPOLB | |
| SCHEMBL9109295 | 0.92 | GHSR (0.49) | GHSRAGTR1XIAPMAPTPOLB | |
| SCHEMBL9105564 | 0.91 | GHSR (0.54) | GHSRAGTR1XIAPMAPTPOLB | |
| SCHEMBL9102858 | 0.91 | GHSR (0.49) | GHSRAGTR1XIAPMAPTPOLB | |
| SCHEMBL9103038 | 0.91 | GHSR (0.48) | GHSRAGTR1XIAPMAPTPOLB | |
| SCHEMBL9105393 | 0.89 | GHSR (0.58) | GHSRAGTR1XIAP | |
| SCHEMBL7795484 | 0.89 | GHSR (0.49) | GHSRAGTR1XIAPKMT2AF7 | |
| SCHEMBL7795658 | 0.89 | GHSR (0.56) | GHSRAGTR1XIAPKMT2AF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430144-A | E.g, N-(1-((2'-((methoxycarbonyl)amino)(1,1'-biphenyl)-4-yl) methyl)-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-3-yl)-3 ((fur-2-yl)methyl)amino-3-methylbutanamide | MERCK & CO., INC. (US) | 1995-07-04 | — | — | US | disclosed |