Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762247 | 0.82 | PTGER1 (0.46) | ALDH1A1GAALPAR1MEN1KMT2A | |
| SCHEMBL16799947 | 0.75 | SLC6A4 (0.45) | ALDH1A1GAAKDM4EHSD17B10MEN1 | |
| SCHEMBL1197183 | 0.74 | POLB (0.42) | ALDH1A1GAAKDM4ERAB9AHSD17B10 | |
| Hydrochloric Acid SCHEMBL4296540 | 0.73 | GABRP (0.42) | ALDH1A1GAAKDM4ERAB9AHSD17B10 | |
| Acetic Acid SCHEMBL16800014 | 0.72 | KDM4E (0.45) | ALDH1A1GAAKDM4EHSD17B10 | |
| SCHEMBL6117734 | 0.71 | SHMT1 (0.34) | ALDH1A1KDM4ERAB9A | |
| SCHEMBL23434997 | 0.71 | HSD17B10 (0.54) | ALDH1A1GAAKDM4ERAB9AHSD17B10 | |
| SCHEMBL26727196 | 0.70 | POLB (0.61) | ALDH1A1GAATSHRMEN1KMT2A | |
| SCHEMBL6118251 | 0.70 | MAPK1 (0.63) | ALDH1A1GAAKDM4ERAB9AHSD17B10 | |
| SCHEMBL23434983 | 0.70 | HPGD (0.43) | ALDH1A1GAAKDM4ERAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460791-A1 | INDOLE DERIVATIVE AND PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-06-06 | — | — | EP | disclosed |