SCHEMBL9103559

SCHEMBL9103559

CCC(N1c2ccccc2Oc2ccc(-c3ncccc3Br)cc21)S(=O)(=O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 2/20 0.31
PIM1 P11309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9102741 0.89 GRIA2 (0.38) P2RX4PIM1
SCHEMBL9102286 0.89 CHRM1 (0.33) P2RX4PIM1
SCHEMBL9105801 0.89 PIM1 (0.35) P2RX4PIM1
SCHEMBL9103943 0.87 CHRM1 (0.32) P2RX4PIM1
SCHEMBL9105077 0.85 APLNR (0.34) PIM1
SCHEMBL9104404 0.83 GRIA2 (0.38)
SCHEMBL9100362 0.83 TP53 (0.33) P2RX4
SCHEMBL9100299 0.83 PDK1 (0.30)
SCHEMBL9100816 0.83 HDAC1 (0.33)
SCHEMBL9103821 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed