SCHEMBL9101955

SCHEMBL9101955

CCCc1cccc2c1Oc1ccccc1N2OS(=O)(=O)CCC

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
P2RX4 Q99571 4/20 0.32
P2RX1 P51575 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9105178 0.93 NR1H2 (0.33) KDM4EPOLBP2RX4P2RX1
SCHEMBL9103561 0.93 KDM4E (0.34) KDM4EPOLBP2RX4P2RX1
SCHEMBL9102956 0.92
SCHEMBL9102996 0.89 P2RX4 (0.36) KDM4EPOLBP2RX4P2RX1
SCHEMBL9104068 0.88 ADRA1D (0.31)
SCHEMBL9105150 0.87 P2RX1 (0.30) P2RX4P2RX1
SCHEMBL9100971 0.85 P2RX4 (0.35) P2RX4P2RX1
SCHEMBL9102681 0.85 MTNR1A (0.32)
SCHEMBL9103893 0.84 P2RX4 (0.33) P2RX4P2RX1
SCHEMBL9104785 0.84 AHR (0.38) KDM4EP2RX4P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed