SCHEMBL9103906

SCHEMBL9103906

CCCCc1cc(CCCC)c2c(c1)Oc1ccccc1N2C(CC)S(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 3/20 0.35
P2RX1 P51575 1/20 0.35
PIM1 P11309 1/20 0.32
METAP2 P50579 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9102598 0.92 P2RX4 (0.34) P2RX4P2RX1PIM1MAPTSMN1; SMN2
SCHEMBL9103487 0.90
SCHEMBL9547674 0.90 METAP2 (0.31) METAP2
SCHEMBL9104492 0.88 P2RX4 (0.37) P2RX4P2RX1PIM1MAPTSMN1; SMN2
SCHEMBL9105608 0.87 P2RX4 (0.33) P2RX4P2RX1PIM1METAP2
SCHEMBL9107440 0.86 P2RX4 (0.36) P2RX4P2RX1PIM1MAPTSMN1; SMN2
SCHEMBL9102028 0.85 P2RX4 (0.38) P2RX4P2RX1PIM1METAP2MAPT
SCHEMBL9104818 0.84 METAP2 (0.33) P2RX4P2RX1METAP2
SCHEMBL9107687 0.84
SCHEMBL9103992 0.83 P2RX4 (0.38) P2RX4P2RX1PIM1METAP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed