SCHEMBL9547674

SCHEMBL9547674

CCCCc1cc(CCCC)c2c(c1)Oc1ccc(CCCC)cc1N2C(CC)S(=O)(=O)O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9100457 0.92
SCHEMBL9104818 0.90 METAP2 (0.33) METAP2
SCHEMBL9103906 0.90 P2RX4 (0.35) METAP2
SCHEMBL9100247 0.86 METAP2 (0.33) METAP2
SCHEMBL9103487 0.86
SCHEMBL9103992 0.83 P2RX4 (0.38) METAP2
SCHEMBL9107687 0.82
SCHEMBL9102598 0.81 P2RX4 (0.34)
SCHEMBL9104702 0.81 METAP2 (0.31) METAP2
SCHEMBL9103659 0.80 METAP2 (0.31) METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed