SCHEMBL9104078

SCHEMBL9104078

CCCc1cccc(-c2cccc3c2N(OS(=O)(=O)CCC)c2ccccc2S3)n1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 1/20 0.32
BCHE P06276 4/20 0.31
MAPT P10636 2/20 0.31
GAA P10253 1/20 0.31
POLB P06746 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9104033 0.94 BCHE (0.34) NOX1BCHE
SCHEMBL9099107 0.94 BCHE (0.32) NOX1BCHEMAPTPOLBSLC6A3
SCHEMBL9105492 0.88 BCHE (0.34) BCHEMAPTSLC6A3
SCHEMBL9105583 0.87 BCHE (0.32) BCHEMAPTSLC6A3
SCHEMBL9099126 0.87 HPGD (0.33) BCHEMAPTGAASLC6A3
SCHEMBL9100398 0.86 NOX1 (0.30) NOX1
SCHEMBL9101269 0.86 BCHE (0.32) NOX1BCHEMAPTPOLB
SCHEMBL9100209 0.83 P2RX1 (0.30) MAPT
SCHEMBL9104286 0.81 BCHE (0.34) BCHEMAPTPOLB
SCHEMBL9100421 0.81 BCHE (0.32) BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed