SCHEMBL9105583

SCHEMBL9105583

CCCS(=O)(=O)ON1c2ccccc2Sc2cccc(-c3cccc(Cl)n3)c21

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BCHE P06276 8/20 0.32
SLC6A3 Q01959 1/20 0.31
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
PDCD1LG2 Q9BQ51 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9099107 0.89 BCHE (0.32) BCHESLC6A3MAPTHTTNPSR1
SCHEMBL9105492 0.89 BCHE (0.34) BCHESLC6A3MAPTHTT
SCHEMBL9099126 0.88 HPGD (0.33) BCHESLC6A3MAPTHTTNPSR1
SCHEMBL9104078 0.87 NOX1 (0.32) BCHESLC6A3MAPT
SCHEMBL9104033 0.85 BCHE (0.34) BCHE
SCHEMBL9102549 0.85 MAPT (0.31) BCHEMAPTHTT
SCHEMBL9100730 0.83 P2RX1 (0.31)
SCHEMBL9100592 0.82 HDAC1 (0.40) BCHEMAPTHTTNPSR1
SCHEMBL9101795 0.80 BCHE (0.35) BCHEMAPTHTT
SCHEMBL9103537 0.79 BCHE (0.31) BCHESLC6A3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed