SCHEMBL9101269

SCHEMBL9101269

CCCc1ccnc(-c2cccc3c2N(OS(=O)(=O)CCC)c2ccccc2S3)n1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.32
MAPT P10636 2/20 0.31
POLB P06746 1/20 0.31
SREBF2 Q12772 1/20 0.31
HTT P42858 1/20 0.30
NOX1 Q9Y5S8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9104286 0.95 BCHE (0.34) BCHEMAPTPOLB
SCHEMBL9101866 0.94 BCHE (0.33) BCHEMAPTPOLBHTT
SCHEMBL9100065 0.89 BCHE (0.33) BCHEMAPTPOLBHTT
SCHEMBL9105126 0.88 HPGD (0.31) BCHEMAPTHTT
SCHEMBL9102549 0.88 MAPT (0.31) BCHEMAPTHTT
SCHEMBL9104078 0.86 NOX1 (0.32) BCHEMAPTPOLBNOX1
SCHEMBL9101679 0.84
SCHEMBL9100398 0.83 NOX1 (0.30) NOX1
SCHEMBL9104033 0.80 BCHE (0.34) BCHENOX1
SCHEMBL9102738 0.80 HDAC3 (0.34) BCHEMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3268489-A1 FLUOROGENIC AND CHROMOGENIC SUBSTRATE LI-COR, INC. (US) 2018-01-17 EP disclosed
US-9632034-B2 Fluorogenic and chromogenic substrate LI-COR, INC. (US) 2017-04-25 US disclosed
WO-2016149127-A1 FLUOROGENIC AND CHROMOGENIC SUBSTRATE LI-COR, INC. (US) 2016-09-22 WO disclosed
US-20160266045-A1 FLUOROGENIC AND CHROMOGENIC SUBSTRATE LI-COR, INC. (US) 2016-09-15 US disclosed
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed