Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.60 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | NOS2 | P35228 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909945 | 0.87 | CYP3A4 (0.63) | TSHRLMNAADRB2CYP3A4GAA | |
| SCHEMBL910622 | 0.84 | STAT3 (0.60) | ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL29604390 | 0.84 | PTPN1 (0.82) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL17780116 | 0.84 | PTPN1 (0.82) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL12076574 | 0.83 | TAAR1 (0.65) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL910751 | 0.83 | TAAR1 (0.64) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL29740697 | 0.82 | PTPN1 (0.79) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL5072123 | 0.80 | TAAR1 (0.76) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL9281549 | 0.80 | TAAR1 (0.76) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL267532 | 0.79 | TAAR1 (0.73) | TAAR1TSHRMAPK1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2020-09-29 | — | — | US | claimed |
| US-20190177366-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | GENENTECH, INC. (US) | 2019-06-13 | — | — | US | claimed |
| US-11034725-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| US-20200283478-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | GENENTECH, INC. (US) | 2020-09-10 | — | — | US | disclosed |
| EP-3031892-B1 | A PROCESS FOR MAKING A CONSUMER GOODS PRODUCT COMPRISING A BENEFIT DELIVERY COMPOSITION | PROCTER & GAMBLE (US) | 2020-02-26 | — | — | EP | disclosed |
| US-20190177366-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | GENENTECH, INC. (US) | 2019-06-13 | — | — | US | disclosed |
| EP-3144375-B1 | A PROCESS FOR MAKING A DETERGENT COMPOSITION | PROCTER & GAMBLE (US) | 2018-12-26 | — | — | EP | disclosed |
| EP-2892620-B1 | MOUTH RINSES AND TOOTH SENSITIVITY TREATMENT COMPOSITIONS | JOHNSON & JOHNSON CONSUMER INC (US) | 2018-05-02 | — | — | EP | disclosed |
| EP-3031893-B1 | A PROCESS FOR MAKING A CONSUMER GOODS PRODUCT COMPRISING A BENEFIT DELIVERY COMPOSITION | PROCTER & GAMBLE (US) | 2017-11-08 | — | — | EP | disclosed |
| US-20170081620-A1 | PROCESS FOR MAKING A DETERGENT COMPOSITION | THE PROCTER & GAMBLE COMPANY | 2017-03-23 | — | — | US | disclosed |
| US-20110004019-A1 | Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2255780-A1 | PARAKERATOSIS INHIBITOR, PORE SHRINKING AGENT OR AGENT FOR PREVENTING OR IMPROVING ROUGH SKIN, AND COMPOSITION FOR EXTERNAL USE ON THE SKIN CONTAINING THE SAME | Shiseido Company, Ltd. (JP) | 2010-12-01 | — | — | EP | disclosed |
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| CN-101557798-A | Compositions comprising combinations of sensates | COLGATE PALMOLIVE CO (US) | 2009-10-14 | — | — | CN | disclosed |
| EP-2088993-A1 | COMPOSITIONS COMPRISING COMBINATIONS OF SENSATES | Colgate-Palmolive Company (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-1941861-A1 | WRINKLE-IMPROVING AGENT | Shiseido Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2008045678-A1 | COMPOSITIONS COMPRISING COMBINATIONS OF SENSATES | COLGATE- PALMOLIVE COMPANY (US) | 2008-04-17 | — | — | WO | disclosed |
| US-20080089850-A1 | Compositions Comprising Combinations of Sensates | COLGATE-PALMOLIVE COMPANY | 2008-04-17 | — | — | US | disclosed |
| EP-1880711-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | TAAR1 1466/4885TSHR 4713/4885MAPK1 2330/4885 |
| US-20200283478-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | PCSK9, PCSK7, PCSK6 | TAAR1 4623/4885TSHR 4184/4885MAPK1 3039/4885 |
| US-20110004019-A1 | Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same | CUTA, GLRA3, ARGLU1 | TAAR1 2774/4885TSHR 2401/4885MAPK1 1877/4885 |
| US-11034725-B2 | Compositions and methods for treating cardiovascular disease | PCSK9, PCSK7, PCSK6 | TAAR1 4623/4885TSHR 4184/4885MAPK1 3039/4885 |
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | PCSK9, PCSK7, PCSK6 | TAAR1 4623/4885TSHR 4184/4885MAPK1 3039/4885 |
| US-20190177366-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | PCSK9, PCSK7, PCSK6 | TAAR1 4623/4885TSHR 4184/4885MAPK1 3039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.