SCHEMBL9104297

SCHEMBL9104297

Nc1c2c(nc3cc(F)ccc13)C1CCC2C1

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACHE P22303 9/20 0.71
BCHE P06276 6/20 0.65
MPO P05164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9107496 0.83 ACHE (0.71) ACHEBCHE
SCHEMBL9107842 0.83 ACHE (1.00) ACHEBCHE
SCHEMBL9106773 0.82 ACHE (0.66) ACHEBCHE
SCHEMBL9105019 0.80 ACHE (0.66) ACHEBCHEMPO
SCHEMBL9106523 0.79 ACHE (1.00) ACHEBCHE
Hydrochloric Acid SCHEMBL10656143 0.78 ACHE (0.97) ACHEBCHE
SCHEMBL9351852 0.76 ACHE (0.46) ACHEBCHE
SCHEMBL9583069 0.75 ACHE (0.67) ACHEBCHE
SCHEMBL9584001 0.74 ACHE (1.00) ACHEBCHE
SCHEMBL9107818 0.74 ACHE (0.71) ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5401749-A Memory enhancers, cholinergic agents HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1995-03-28 US claimed
US-5401749-A Memory enhancers, cholinergic agents HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1995-03-28 US disclosed