Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.69 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.48 |
| ▸ | TMPRSS15 | P98073 | 9/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305759 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2B | |
| SCHEMBL1710973 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL7431004 | 0.85 | ITGB3 (0.70) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL7438806 | 0.83 | ITGB3 (0.71) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL7306316 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| Acetic Acid SCHEMBL9097876 | 0.83 | ITGB3 (0.68) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| Hydrochloric Acid SCHEMBL9435247 | 0.82 | ITGB3 (0.70) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9103107 | 0.82 | ITGB3 (0.70) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL7379987 | 0.82 | ITGB3 (1.00) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL7379869 | 0.82 | ITGB3 (1.00) | ITGB3ITGA2BPRSS1TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5481021-A | Phenyl amidines derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-01-02 | — | — | US | claimed |
| EP-0574545-B1 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1994-11-30 | — | — | EP | claimed |
| US-5481021-A | Phenyl amidines derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0574545-B1 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1994-11-30 | — | — | EP | disclosed |