SCHEMBL1710973

SCHEMBL1710973

CC(C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)CCCOc1ccc(C(=N)N)cc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 3/20 0.48
ITGA2B P08514 3/20 0.48
PRSS1 P07477 14/20 0.48
TMPRSS15 P98073 14/20 0.48
PPARG P37231 2/20 0.47
PPARA Q07869 1/20 0.47
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9104411 0.85 ITGB3 (0.69) ITGB3ITGA2BPRSS1TMPRSS15
SCHEMBL7305759 0.84 ITGB3 (0.54) ITGB3ITGA2B
SCHEMBL7306316 0.82 ITGB3 (0.51) ITGB3ITGA2BPRSS1TMPRSS15
Trifluoroacetic Acid SCHEMBL9217427 0.80 ITGB3 (0.49) ITGB3ITGA2B
SCHEMBL9296637 0.78 ITGB3 (0.46) ITGB3ITGA2BPRSS1TMPRSS15
Trifluoroacetic Acid SCHEMBL7308419 0.77 ITGB3 (0.46) ITGB3ITGA2B
SCHEMBL7338778 0.77 ITGB3 (0.46) ITGB3ITGA2BPRSS1TMPRSS15NPSR1
SCHEMBL7748657 0.77 PRSS1 (0.71) ITGB3ITGA2BPRSS1
SCHEMBL8830329 0.77 ITGB3 (0.41) ITGB3ITGA2BPRSS1TMPRSS15
SCHEMBL7441948 0.75 EPHX2 (0.44) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3157408-B1 DEVICES TO PROVIDE HANDS FREE SCLERAL DEPRESSION DURING OPHTHALMIC PROCEDURES ALCON INC (CH) 2026-03-25 EP disclosed
EP-4714407-A2 DEVICES TO PROVIDE HANDS FREE SCLERAL DEPRESSION DURING OPHTHALMIC PROCEDURES Alcon Inc. (CH) 2026-03-25 EP disclosed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
US-20250057694-A1 DEVICES AND METHODS TO PROVIDE HANDS FREE SCLERAL DEPRESSION AND ILLUMINATION DURING OPHTHALMIC PROCEDURES Ganihand, LLC (US) 2025-02-20 US disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
US-11266395-B2 Devices and methods to provide hands free scleral depression during ophthalmic procedures Ganihand, LLC (US) 2022-03-08 US disclosed
EP-1481966-B1 NOVEL ARYLAMIDINE DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO LTD (JP) 2011-07-20 EP disclosed
US-20070189970-A1 Contrast medium for thrombus formation ASTELLAS PHARMA INC. (JP) 2007-08-16 US disclosed
US-20070189970-A1 Contrast medium for thrombus formation ASTELLAS PHARMA INC. (JP) 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070189970-A1 Contrast medium for thrombus formation FGB, F13B, TFPI ITGB3 36/4885ITGA2B 17/4885PRSS1 1697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.