Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 7/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.46 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.45 |
| ▸ | ATG7 | O95352 | 5/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10067432 | 0.91 | ADK (0.48) | ADKPRMT5METTL3ATG7DOT1L | |
| SCHEMBL12405891 | 0.87 | ADK (0.57) | ADKDOT1L | |
| SCHEMBL91049 | 0.87 | RXFP1 (0.43) | ADKPRMT5METTL3ATG7 | |
| SCHEMBL12522464 | 0.83 | ADK (0.60) | ADKPRMT5METTL3ATG7DOT1L | |
| SCHEMBL10067434 | 0.78 | RXFP1 (0.41) | ADKPRMT5METTL3ATG7DOT1L | |
| SCHEMBL12405887 | 0.78 | ADK (0.52) | ADKDOT1L | |
| SCHEMBL10067433 | 0.76 | PI4KA (0.54) | ADKDOT1L | |
| SCHEMBL12374617 | 0.73 | ADK (0.62) | ADKPRMT5DOT1LPRMT3DNMT1 | |
| SCHEMBL91052 | 0.73 | SLC29A1 (0.58) | DOT1L | |
| SCHEMBL1228087 | 0.72 | AHCY (0.72) | DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129106-B2 | Sequence-specific detection of methylation in biomolecules | Max-Planck-Geselischaft zur Forderung der Wissenschaften E.V. (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20110165564-A1 | SEQUENCE-SPECIFIC DETECTION OF METHYLATION IN BIOMOLECULES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165564-A1 | SEQUENCE-SPECIFIC DETECTION OF METHYLATION IN BIOMOLECULES | DNMT1, MAT2B, AHCY | ADK 291/4885PRMT5 43/4885METTL3 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.