SCHEMBL9105233

SCHEMBL9105233

CCCS(=O)(=O)ON1c2cccc(CC)c2Oc2cccc(CC)c21

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.30
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9103561 0.91 KDM4E (0.34) MAOAKDM4EPOLB
SCHEMBL9102956 0.90
SCHEMBL9101934 0.90 P2RX4 (0.36) MAOAKDM4EPOLB
SCHEMBL9105939 0.88
SCHEMBL9102681 0.88 MTNR1A (0.32)
SCHEMBL9105475 0.87
SCHEMBL9101955 0.84 KDM4E (0.33) KDM4EPOLB
SCHEMBL9103488 0.83 KDM4E (0.30) KDM4E
SCHEMBL9102996 0.82 P2RX4 (0.36) MAOAKDM4EPOLB
SCHEMBL9102548 0.82 MAPT (0.30) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed