SCHEMBL9105236

SCHEMBL9105236

CCCS(=O)(=O)ON1c2ccc(C)cc2Sc2c(C)cccc21

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 1/20 0.31
BCHE P06276 1/20 0.31
KDM4E B2RXH2 3/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 2/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 2/20 0.30
F2 P00734 2/20 0.30
MAPT P10636 2/20 0.30
XBP1 P17861 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9100982 0.88 BCHE (0.38) BCHEPOLBKMT2AMEN1MAPT
SCHEMBL9102428 0.86 BCHE (0.41) DRD3BCHEKDM4EKMT2AMEN1
SCHEMBL9100000 0.85 NR3C1 (0.31)
SCHEMBL9102563 0.82 BCHE (0.32) BCHEKMT2AMEN1
SCHEMBL9104058 0.82 BCHE (0.32) BCHEPOLBKMT2A
SCHEMBL9102104 0.81 BCHE (0.36) BCHEKDM4EKMT2AMEN1ALDH1A1
SCHEMBL9104158 0.79 BCHE (0.41) BCHEKMT2AALDH1A1MAPTHTT
SCHEMBL9102178 0.79 KDM4E (0.30) KDM4EALDH1A1F2MAPT
SCHEMBL9104980 0.77
SCHEMBL9101005 0.76 NR3C1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed