SCHEMBL9102549

SCHEMBL9102549

CCCS(=O)(=O)ON1c2ccccc2Sc2cccc(-c3nccc(Cl)n3)c21

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
BCHE P06276 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9100065 0.90 BCHE (0.33) MAPTHTTBCHE
SCHEMBL9101866 0.90 BCHE (0.33) MAPTHTTBCHE
SCHEMBL9105126 0.89 HPGD (0.31) MAPTHTTBCHE
SCHEMBL9101269 0.88 BCHE (0.32) MAPTHTTBCHE
SCHEMBL9104286 0.86 BCHE (0.34) MAPTBCHE
SCHEMBL9105583 0.85 BCHE (0.32) MAPTHTTBCHE
SCHEMBL9101809 0.84 USP2 (0.31)
SCHEMBL9101795 0.82 BCHE (0.35) MAPTHTTBCHE
SCHEMBL9100592 0.79 HDAC1 (0.40) MAPTHTTBCHE
SCHEMBL9104104 0.79 THRB (0.36) MAPTHTTBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed