Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 9/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9104587 | 0.95 | GHSR (0.58) | GHSRAGTR1XIAPNPY1RCCKBR | |
| SCHEMBL9104909 | 0.94 | GHSR (0.59) | GHSRAGTR1XIAPNPY1RCCKBR | |
| SCHEMBL9108345 | 0.93 | GHSR (0.51) | GHSRAGTR1XIAPNPY1RCCKBR | |
| SCHEMBL9103719 | 0.92 | GHSR (0.59) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL9109371 | 0.91 | GHSR (0.69) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL9107203 | 0.91 | GHSR (0.58) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL9105393 | 0.91 | GHSR (0.58) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL9103038 | 0.89 | GHSR (0.48) | GHSRAGTR1XIAP | |
| SCHEMBL7791881 | 0.89 | GHSR (0.60) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL7786070 | 0.88 | GHSR (0.59) | GHSRAGTR1XIAPNPY1RCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430144-A | E.g, N-(1-((2'-((methoxycarbonyl)amino)(1,1'-biphenyl)-4-yl) methyl)-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-3-yl)-3 ((fur-2-yl)methyl)amino-3-methylbutanamide | MERCK & CO., INC. (US) | 1995-07-04 | — | — | US | disclosed |