Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105781 | 1.00 | HIF1A (0.45) | HIF1AADORA3ADORA2AADRB1DNMT1 | |
| SCHEMBL9108339 | 0.82 | HIF1A (0.46) | HIF1AADORA3ADORA2ASLC29A1 | |
| SCHEMBL9108355 | 0.82 | HIF1A (0.46) | HIF1AADORA3ADORA2ASLC29A1 | |
| SCHEMBL5983124 | 0.81 | ADORA3 (0.52) | HIF1AADORA3ADORA2AADRB1DNMT1 | |
| SCHEMBL31685786 | 0.81 | ADORA3 (0.52) | HIF1AADORA3ADORA2AADRB1DNMT1 | |
| SCHEMBL5983113 | 0.81 | ADORA3 (0.52) | HIF1AADORA3ADORA2AADRB1DNMT1 | |
| SCHEMBL24420487 | 0.79 | ADORA3 (0.66) | HIF1AADORA3ADORA2AADRB1DNMT1 | |
| SCHEMBL13835070 | 0.79 | ADORA3 (0.66) | HIF1AADORA3ADORA2AADRB1DNMT1 | |
| SCHEMBL6302264 | 0.79 | ADORA3 (0.66) | HIF1AADORA3ADORA2AADRB1DNMT1 | |
| SCHEMBL30274706 | 0.79 | ADORA3 (0.66) | HIF1AADORA3ADORA2AADRB1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558634-A4 | TRIPLEX-FORMING OLIGOMERS CONTAINING MODIFIED BASES | GILEAD SCIENCES INC (US) | 1995-06-28 | — | — | EP | disclosed |
| EP-0558634-A1 | TRIPLEX-FORMING OLIGOMERS CONTAINING MODIFIED BASES | GILEAD SCIENCES, INC. (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992010590-A1 | INHIBITION OF TRANSCRIPTION BY FORMATION OF TRIPLE HELIXES | GILEAD SCIENCES, INC. (US) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992009705-A1 | TRIPLEX-FORMING OLIGOMERS CONTAINING MODIFIED BASES | GILEAD SCIENCES, INC. (US) | 1992-06-11 | — | — | WO | disclosed |