Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105928 | 1.00 | HIF1A (0.47) | HIF1AADORA3ADORA2ASLC29A1ADK | |
| SCHEMBL9108372 | 0.88 | HIF1A (0.48) | HIF1AADORA3ADORA2ASLC29A1ADK | |
| SCHEMBL5983118 | 0.88 | HSPA5 (0.52) | HIF1AADORA3ADORA2ASLC29A1HSPA5 | |
| SCHEMBL9108380 | 0.88 | HIF1A (0.48) | HIF1AADORA3ADORA2ASLC29A1ADK | |
| SCHEMBL5983106 | 0.88 | HSPA5 (0.52) | HIF1AADORA3ADORA2ASLC29A1HSPA5 | |
| SCHEMBL5983406 | 0.87 | ADK (0.49) | HIF1AADORA3ADORA2AADKRXFP1 | |
| SCHEMBL9109579 | 0.87 | HIF1A (0.50) | HIF1AADORA3ADORA2ASLC29A1ADK | |
| SCHEMBL9109570 | 0.87 | HIF1A (0.50) | HIF1AADORA3ADORA2ASLC29A1ADK | |
| SCHEMBL5983403 | 0.87 | ADK (0.49) | HIF1AADORA3ADORA2AADKRXFP1 | |
| SCHEMBL7197458 | 0.84 | ADORA3 (0.64) | HIF1AADORA3ADORA2AHSPA5HSPA8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558634-A4 | TRIPLEX-FORMING OLIGOMERS CONTAINING MODIFIED BASES | GILEAD SCIENCES INC (US) | 1995-06-28 | — | — | EP | disclosed |
| EP-0558634-A1 | TRIPLEX-FORMING OLIGOMERS CONTAINING MODIFIED BASES | GILEAD SCIENCES, INC. (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992009705-A1 | TRIPLEX-FORMING OLIGOMERS CONTAINING MODIFIED BASES | GILEAD SCIENCES, INC. (US) | 1992-06-11 | — | — | WO | disclosed |