SCHEMBL9106521

SCHEMBL9106521

CCCc1cc(CCC)c2c(c1)Oc1c(CCC)cccc1N2CCCS(=O)(=O)O

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
MAPT P10636 4/20 0.34
POLB P06746 4/20 0.34
MMP13 P45452 3/20 0.34
HPGD P15428 4/20 0.32
ALOX15 P16050 2/20 0.32
ALOX12 P18054 2/20 0.32
CASP1 P29466 2/20 0.32
HSD17B10 Q99714 2/20 0.32
LMNA P02545 1/20 0.32
CASP7 P55210 1/20 0.32
ALDH1A1 P00352 3/20 0.31
TDP1 Q9NUW8 3/20 0.31
ALPG P10696 2/20 0.31
MAPK1 P28482 2/20 0.31
PKM P14618 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9103489 0.93 MEN1 (0.34) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9102378 0.90 MEN1 (0.32) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9102942 0.90 MAPT (0.35) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9102607 0.88 SIGMAR1 (0.38) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9104061 0.87 MAPT (0.33) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9105933 0.87 MAPT (0.36) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9102674 0.84 MTNR1A (0.35) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9100474 0.84 MEN1 (0.32) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9101949 0.83 SIGMAR1 (0.38) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9107692 0.83 S1PR2 (0.33) MEN1KMT2AMAPTPOLBMMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed